February 6, 2024- New Cleveland Clinic research has mapped changes in tumor-related bacteria to uncover potential new strategies to combat the rise of young-onset colorectal cancer (CRC) in people under the age of 50.
The research reveals differences in tumor-related bacteria associated with young-onset colorectal cancer. Published in eBioMedicine (part of Lancet Discovery Science), the findings could lead to new screenings or treatments for this population.
According to the American Cancer Society, the incidence and mortality of young-onset colorectal cancer have increased by 1.5% and 1.2% per year, respectively. If this trend continues, a Journal of the National Cancer Institute report estimates the incidence of colon cancer would double and rectal cancer would quadruple in this age group by 2030. Further research is needed into how lifestyle factors may impact gut bacteria.