PCORI launches pioneering initiative offering $50m to boost uptake of practice-changing health research findings in real-world settings 

Doctor In Consultation With Female Patient In Office

March 10, 2023 – The Patient-Centered Outcomes Research Institute kicked off a multiyear initiative with an initial investment of $50 million to advance the uptake of practice-changing comparative clinical effectiveness research results into health care practice with the selection of 42 U.S. health systems to participate in its groundbreaking Health Systems Implementation Initiative (HSII). In addition, PCORI initiated the first of two stages of HSII funding, focusing on initial capacity-building efforts. 

The array of participating health systems representing a wide range of care settings and populations will develop and implement viable strategies to actively advance the adoption of new evidence in health care delivery. PCORI’s unique approach of supporting health systems directly in dissemination and implementation expands the organization’s work in this area and demonstrates its leadership in efforts to cut the estimated 17-year lag between the publication of results and their uptake in practice. 

In addition to announcing participants, PCORI has opened the first HSII funding opportunity for participating health systems to propose capacity-building projects, with awards to be announced this summer. Each participating health system can receive up to $500,000 for a project that supports preparation for future implementation strategies and program evaluation. Subsequent HSII funding opportunities will support innovative implementation projects that promote the uptake of specific evidence from PCORI-funded research studies within the health systems, with funds ranging from $500,000 to $5 million per project. 

HSII participants collectively represent 800 hospitals serving 79 million unique patients—nearly a quarter of the U.S. population—across 41 states and the District of Columbia. They include academic medical centers, community-based systems, integrated health care delivery and finance systems, safety net health systems, faith-based systems, public health care delivery systems, and a medical center within the Veterans Health Administration. See the complete list. 

HSII participants will collaborate in a learning network established by PCORI to share experiences and learn from one another about best practices for implementation, evaluation metrics and other topics integral to the initiative’s success. Through the network, PCORI will seek input from network participants on topics and specific findings from PCORI-funded studies that are of interest for future implementation projects. 

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