March 22, 2023 – Abbott announced new data that found monitoring patients remotely with hemodynamic pressure sensing technology, such as with its CardioMEMS™ HF System, can significantly improve survival in heart failure patients with reduced ejection fraction (HFrEF). The analysis is the first to give doctors specific insight into how remotely monitoring patients with technology like CardioMEMS can provide an early warning against worsening heart failure and significantly reduce mortality risk by 25% at two years in HFrEF patients.
The CardioMEMS sensor is a paperclip-sized device that, once placed in the pulmonary artery during a minimally invasive procedure, monitors for pressure changes that indicate worsening heart failure. It wirelessly transmits daily readings to a patient’s clinical team – empowering the patient and their care team to manage their condition from virtually anywhere. HFrEF, the type of heart failure assessed within the latest meta-analysis, occurs when the heart muscle is weakened and not able to pump out enough blood for the body, representing roughly half3 of all cases of heart failure.
Within the new analysis, data from the CHAMPION, GUIDE-HF and LAPTOP-HF4 trials were combined to assess the mortality and heart failure hospitalizations of 1,350 HFrEF patients. Among the three randomized trials, more than 650 patients were subjected to hemodynamic monitoring and 684 received the control. Heart failure hospitalizations were analyzed over a 12-month follow-up period and all-cause mortality was evaluated across 24 months.
The meta-analysis validated that hemodynamic monitoring can slow the progression of heart failure in HFrEF patients by significantly decreasing heart failure-related hospitalizations and improving survival.